Cardiac hypertrophy and atrophy

What Atrophy, Hypertrophy, and Cardiac Failure Have in Common

Proteins in cardiac and skeletal muscle cells, as in other cells, are continually being synthesized and degraded back to their constituent amino acids. Protein turnover in cardiac myocytes utilizes the same proteolytic systems as other eukaryotic cells: the ubiquitin-proteasome pathway, which catalyzes the rapid degradation of misfolded and regulatory proteins, and the lysosomal-autophagic syst...

Detection of Cardiac Hypertrophy by RVM and SVM Algorithms

The meaning of the hypertropy word is the increasing size.Heart hypertropy is symptoms of increase the thickness of the heart muscle that the left ventricular hypertrophy of them is the most common.The causes of hypertrophy heart disease are high blood pressure , aortic valve stenosis and sport activities respectively. Assessment of that by using ECG signal analysis is essential Because the ris...

Signaling in muscle atrophy and hypertrophy.

Muscle performance is influenced by turnover of contractile proteins. Production of new myofibrils and degradation of existing proteins is a delicate balance, which, depending on the condition, can promote muscle growth or loss. Protein synthesis and protein degradation are coordinately regulated by pathways that are influenced by mechanical stress, physical activity, availability of nutrients,...

Bilateral trapezius hypertrophy with dystonia and atrophy.

Myosin heavy chain synthesis is independently regulated in hypertrophy and atrophy of isolated adult cardiac myocytes.

Hypertrophy of isolated adult feline cardiac muscle cells may be induced in culture by either alpha- or beta-adrenergic agonists. However, it has been shown previously that each of these agonists activate different subsets of immediate-early response genes and have different effects on expression of "fetal" protein isoforms and stimulation of protein synthesis. Moreover, in adult feline heart c...